Award: M&M team awarded MBSANZ paper(s) of the year

Thomas R. Cox, Feb 2020


The Matrix Biology Society of Australia and New Zealand (MBSANZ) has just announced their “Paper of the Year” awards in the Early Career Research (ECR) and Mid Career Researcher (MCR) categories.

We are delighted that two papers from the Matrix & Metastasis lab and collaborators have been chosen for these awards

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Publication: Cancer Metastasis: The Role of the Extracellular Matrix and the Heparan Sulfate Proteoglycan Perlecan

Thomas R. Cox, Jan 2020

Cancer Metastasis: The Role of the Extracellular Matrix and the Heparan Sulfate Proteoglycan Perlecan

Our recent review paper in collaboration with colleagues in Sydney and Melbourne on the role of the ECM and in particular the Heparan Sulphate Proteoglycan, Perlecan, in cancer and cancer metastasis, has just been published in Frontiers in Oncology.

Perlecan (HSPG2) in Cancer

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People: Our newest M&M starter – Kaitlin

Thomas R. Cox, Jan 2020

We are pleased to announce that Kaitlin Wyllie has just joined the Matrix & Metastasis team as a Research Assistant.
Kaitlin Wyllie - Matrix & Metastasis

Kaitlin recently completed her Master of Research (M.Res.) at the Department of Molecular Sciences at Macquarie University.

Kaitlin will join our projects looking at the role of the ECM in breast cancer therapy and our efforts to develop novel targeting approaches.


People: First Class Honours all round…

Thomas R. Cox, Dec 2019

I am delighted to share the news that our two wonderful Honours Students for 2019, Yordanos Setargew and Shivanjali Ratnaseelan have both been awarded First Class Honours from the School of Medical Sciences at UNSW Sydney. Yordanos for her project on “Targeting lysyl oxidase driven fibrosis in pancreatic ductal adenocarcinoma via copper inhibition” and Shivanjali for her project on the “Role of Extracellular Matrix Stiffness on Tumor Cell Response to Therapy”

Congratulations to both đŸ™‚


Publication: Targeting the lysyl oxidases in tumour desmoplasia

Thomas R. Cox, Nov 2019

Targeting the lysyl oxidases in tumour desmoplasia

Our recent review discussing the importance, and also the therapeutic potential of inhibiting the lysyl oxidase (LOX) family of enzymes as a stromal targeting therapy has just been published in Biochemical Society Transactions.

The Lysyl Oxidase (LOX) Family

The Lysyl Oxidase (LOX) family of enzymes

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Award: St Vincent’s Clinic Foundation Award to Elysse

Thomas R. Cox, Nov 2019

I’m delighted to announce that Elysse from the Matrix and Metastasis Team has just been awarded the St Vincent’s Clinic Foundation K&A Collins Cancer Research Award.

Elysse_SVCF_AwardThe St Vincent’s Clinic Foundation was established in 1992 to further the educational and research objectives of St Vincent’s Clinic and the surrounding precinct. The Foundation provides much-needed seed funding towards real research projects for real people including medical, basic and multidisciplinary research. The Awards are given to support bright young researchers who can put their research into real-world practise to improve patient care and health outcomes for the community.

The award which was announced at the annual Sandra David Oration, will give Elysse the opportunity (and $50,000 of seed funding) to further her novel work to find new and effective treatments for breast cancer to improve the clinical care and outcomes for patients.

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People: Research Assistant position available to start late 2019/early 2020

Thomas R. Cox, Oct 2019


We are seeking a full-time dedicated Research Assistant (RA) to come work with us.  The group combines the use of 3D models of cancer with novel state-of-the-art imaging approaches to reveal how the extracellular matrix (ECM) drives cancer progression and metastasis. Our mission is to establish targeting of the extracellular matrix as a viable therapeutic approach in the treatment of solid cancers.

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