Category Archives: Pancreatic Cancer

Publication: Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis

Thomas R. Cox, Apr 2017

ROCK-ing pancreatic cancer to the core

Our new paper on short-term pulsed treatment, or ‘priming’ as a treatment strategy to boost chemotherapy has just been published in Science Translational Medicine.

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STM Front Cover Vol 9 Issue 384 (Image: Timpson Laboratory, Garvan Institute)

 

The research, spearheaded by Dr. Paul Timpson and Dr. Marina Pajic here at the Garvan Institute of Medical Research in Sydney, has uncovered a promising new approach to treating pancreatic cancer. By targeting the tissue surrounding the tumour to make it ‘softer’, it leads to tumours being more responsive to chemotherapy.

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Publication: Tissue Fibrosis and Pancreatic Cancer

Thomas R. Cox, Jun 2016

Fibrosis and Cancer: Partners in Crime or Opposing Forces?

Our recent forum discussing the importance of cancer associated fibrosis in pancreatic cancer has just been published in Trends in Cancer

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Targeting the Extracellular Matrix (ECM) in Pancreatic Ductal Adenocarcinoma (PDAC).

What is cancer associated fibrosis?

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